Aric Prather, PhD

AME center Director

Dr. Prather is an Assistant Professor of Psychiatry at UCSF. His research focuses on complex interactions between psychological processes and sleep as they relate to physical and mental illness. With expertise in psychoneuroimmunology (PNI), much of his research involves understanding how psychosocial factors affect the immune system, with emphasis on inflammatory pathways as a key biological mechanism.

Dr. Prather received his Ph.D. in Clinical and Biological & Health Psychology at the University of Pittsburgh in August 2010 following completion of his Clinical Psychology Pre-doctoral Internship at Duke University Medical Center. Prior to his Ph.D. he received a Master of Science in Psychology from the University of Pittsburgh in 2006 and a Bachelor of Arts in Psychology from the University of California, Berkeley in 2001.

Peer Reviewed Publications

28. Puterman E, Gemmill A, Karasek D, Weir D, Adler NEPrather AAEpel ES. Lifespan adversity and later adulthood telomere length in the nationally representative US Health and Retirement Study. Proc Natl Acad Sci U S A. 2016 Oct 18; 113(42):E6335-E6342. PubMed 

27. Prather AA, Janicki-Deverts D, Adler NE, Hall M, Cohen S, et al. Sleep Habits and Susceptibility to Upper Respiratory Illness: the Moderating Role of Subjective Socioeconomic Status. Ann Behav Med. 2016 Sep 27. PubMed 

26. Giuse NB, Koonce TY, Kusnoor SV, Prather AA, Gottlieb LM, Huang LC, Phillips SE, Shyr Y, Adler NE, Stead WW, et al. Institute of Medicine Measures of Social and Behavioral Determinants of Health: A Feasibility Study. Am J Prev Med. 2016 Sep 19. PubMed 

25. Swartz JR, Prather AA, Di Iorio CR, Bogdan R, Hariri AR, et al. A Functional Interleukin-18 Haplotype Predicts Depression and Anxiety Through Increased Threat-Related Amygdala Reactivity in Women but not Men. Neuropsychopharmacology. 2016 Jul 19. PubMed 

24. Prather AA, Leung CW. Association of Insufficient Sleep With Respiratory Infection Among Adults in the United States. JAMA Intern Med. 2016 Jun 1; 176(6):850-2. PubMed 

23. Baranger DA, Ifrah C, Prather AA, Carey CE, Corral-Frías NS, Drabant Conley E, Hariri AR, Bogdan R. PER1 rs3027172 Genotype Interacts with Early Life Stress to Predict Problematic Alcohol Use, but Not Reward-Related Ventral Striatum Activity. Front Psychol. 2016; 7:464. PubMed 

22. Prather AAHecht FMEpel ES. Factors related to telomere length. Brain Behav Immun. 2016 Mar; 53:279. PubMed 

21. Prather AA, Janicki-Deverts D, Hall MH, Cohen S. Behaviorally Assessed Sleep and Susceptibility to the Common Cold. Sleep. 2015 Sep; 38(9):1353-9. PubMed | PubMed Central 

20. Adler NEPrather AA. Risk for Type 2 Diabetes Mellitus: Person, Place, and Precision Prevention. JAMA Intern Med. 2015 Aug; 175(8):1321-2. PubMed 

19. Prather AAEpel ES, Arenander J, Broestl L, Garay BI, Wang D, Dubal DB. Longevity factor klotho and chronic psychological stress. Transl Psychiatry. 2015; 5:e585. PubMed | PubMed Central 

18. Prather AAGurfein B, Moran P, Daubenmier J, Acree M, Bacchetti PSinclair E, Lin JBlackburn EHecht FMEpel ES. Tired telomeres: Poor global sleep quality, perceived stress, and telomere length in immune cell subsets in obese men and women. Brain Behav Immun. 2015 Jul; 47:155-62. PubMed | PubMed Central 

17. Puterman EEpel ESO'Donovan APrather AAAschbacher K, Dhabhar FS. Anger is associated with increased IL-6 stress reactivity in women, but only among those low in social support. Int J Behav Med. 2014 Dec; 21(6):936-45. PubMed | PubMed Central 

16. Prather AA, Vogelzangs N, Penninx BW. Sleep duration, insomnia, and markers of systemic inflammation: results from the Netherlands Study of Depression and Anxiety (NESDA). J Psychiatr Res. 2015 Jan; 60:95-102. PubMed | PubMed Central 

15. Prather AAPuterman E, Epel ES, Dhabhar FS. Poor sleep quality potentiates stress-induced cytokine reactivity in postmenopausal women with high visceral abdominal adiposity. Brain Behav Immun. 2014 Jan; 35:155-62. PubMed | PubMed Central 

14. Prather AAEpel ESCohen BENeylan TCWhooley MA. Gender differences in the prospective associations of self-reported sleep quality with biomarkers of systemic inflammation and coagulation: findings from the Heart and Soul Study. J Psychiatr Res. 2013 Sep; 47(9):1228-35. PubMed | PubMed Central 

13. Prather AA, Bogdan R, Hariri AR. Impact of sleep quality on amygdala reactivity, negative affect, and perceived stress. Psychosom Med. 2013 May; 75(4):350-8. PubMed | PubMed Central 

12. Prather AA, Hall M, Fury JM, Ross DC, Muldoon MF, Cohen S, Marsland AL. Sleep and antibody response to hepatitis B vaccination. Sleep. 2012 Aug; 35(8):1063-9. PubMed | PubMed Central 

11. Aschbacher KEpel EWolkowitz OMPrather AAPuterman EDhabhar FS. Maintenance of a positive outlook during acute stress protects against pro-inflammatory reactivity and future depressive symptoms. Brain Behav Immun. 2012 Feb; 26(2):346-52. PubMed | PubMed Central 

10. Prather AAPuterman E, Lin J, O'Donovan A, Krauss J, Tomiyama AJ, Epel ESBlackburn EH. Shorter leukocyte telomere length in midlife women with poor sleep quality. J Aging Res. 2011; 2011:721390. PubMed | PubMed Central 

9. Prather AABlumenthal JA, Hinderliter AL, Sherwood A. Ethnic differences in the effects of the DASH diet on nocturnal blood pressure dipping in individuals with high blood pressure. Am J Hypertens. 2011 Dec; 24(12):1338-44. PubMed | PubMed Central 

8. Carroll JE, Low CA, Prather AA, Cohen S, Fury JM, Ross DC, Marsland AL. Negative affective responses to a speech task predict changes in interleukin (IL)-6. Brain Behav Immun. 2011 Feb; 25(2):232-8. PubMed | PubMed Central

7. Okun ML, Luther J, Prather AA, Perel JM, Wisniewski S, Wisner KL. Changes in sleep quality, but not hormones predict time to postpartum depression recurrence. J Affect Disord. 2011 May; 130(3):378-84. PubMed | PubMed Central 

6. Prather AA, Rabinovitz M, Pollock BG, Lotrich FE. Cytokine-induced depression during IFN-alpha treatment: the role of IL-6 and sleep quality. Brain Behav Immun. 2009 Nov; 23(8):1109-16. PubMed | PubMed Central

5. Prather AA, Marsland AL, Hall M, Neumann SA, Muldoon MF, Manuck SB. Normative variation in self-reported sleep quality and sleep debt is associated with stimulated pro-inflammatory cytokine production. Biol Psychol. 2009 Sep; 82(1):12-7. PubMed | PubMed Central

4. Prather AA, Carroll JE, Fury JM, McDade KK, Ross D, Marsland AL. Gender differences in stimulated cytokine production following acute psychological stress. Brain Behav Immun. 2009 Jul; 23(5):622-8. PubMed | PubMed Central

3. Marsland AL, Prather AA, Petersen KL, Cohen S, Manuck SB. Antagonistic characteristics are positively associated with inflammatory markers independently of trait negative emotionality. Brain Behav Immun. 2008 Jul; 22(5):753-61. PubMed | PubMed Central

2. Marsland AL, Gianaros PJ, Prather AA, Jennings JR, Neumann SA, Manuck SB. Stimulated production of proinflammatory cytokines covaries inversely with heart rate variability. Psychosom Med. 2007 Nov; 69(8):709-16. PubMed 

1. Prather AA, Marsland AL, Muldoon MF, Manuck SB. Positive affective style covaries with stimulated IL-6 and IL-10 production in a middle-aged community sample. Brain Behav Immun. 2007 Nov; 21(8):1033-7. PubMed | PubMed Central